Phosphorylated Hexaacyl Disaccharides Augment Host Resistance Against Common Nosocomial Pathogens

OBJECTIVES: To determine whether synthetic phosphorylated hexaacyl disaccharides (PHADs) provide antimicrobial protection in clinically relevant models of bacterial infection. DESIGN: Laboratory study. SETTING: University laboratory. SUBJECTS: BALB/c, C57BL/10J, and C57BL/10ScNJ mice. INTERVENTIONS:...

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Published in:Crit Care Med
Main Authors: Hernandez, Antonio, Luan, Liming, Stothers, Cody L., Patil, Naeem K., Fults, Jessica B., Fensterheim, Benjamin A., Guo, Yin, Wang, Jingbin, Sherwood, Edward R., Bohannon, Julia K.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791756/
https://ncbi.nlm.nih.gov/pubmed/31567352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000003967
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