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Evidence for interaction of the NLRP3 inflammasome and Bruton’s tyrosine kinase in tumor-associated macrophages: implications for myeloid cell production of interleukin-1beta

An inflammatory microenvironment has been shown to play an important role in the growth and metastasis of tumors. The NLRP3 inflammasome is a multi-protein complex of the innate immune system that is responsible for the production of the potent inflammatory cytokine IL-1β. Tumor- associated macropha...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Benner, Brooke, Scarberry, Luke, Stiff, Andrew, Duggan, Megan C., Good, Logan, Lapurga, Gabriella, Butchar, Jonathan P., Tridandapani, Susheela, Carson, William E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791459/
https://ncbi.nlm.nih.gov/pubmed/31646085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1659704
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