Upregulation of intratumoral HLA class I and peritumoral Mx1 in ulcerated melanomas

Before the era of immune checkpoint blockade, a meta-analysis encompassing fifteen trials reported that adjuvant IFN-α significantly reduces the risk of relapse and improves survival of ulcerated melanoma (UM) with no benefit for higher doses compared to lower doses. IFNa2b affects many cell intrins...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Verver, Daniëlle, Poirier-Colame, Vichnou, Tomasic, Gorana, Cherif-Rebai, Khadija, Grunhagen, Dirk J., Verhoef, Cornelis, Suciu, Stefan, Robert, Caroline, Zitvogel, Laurence, Eggermont, Alexander M.M.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2019
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791452/
https://ncbi.nlm.nih.gov/pubmed/31646109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1660121
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