Imaging the intratumoral-peritumoral extracellular pH gradient of gliomas

Solid tumors have acidic extracellular pH (pH(e)) but near neutral intracellular pH (pH(i)). Because acidic pH(e) milieu is conducive to tumor growth and builds resistance to therapy, simultaneous mapping of pH(e) inside and outside the tumor (i.e., intratumoral-peritumoral pH(e) gradient) fulfills...

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Detalhes bibliográficos
Publicado no:NMR Biomed
Main Authors: Coman, Daniel, Huang, Yuegao, Rao, Jyotsna U., De Feyter, Henk M., Rothman, Douglas L., Juchem, Christoph, Hyder, Fahmeed
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769673/
https://ncbi.nlm.nih.gov/pubmed/26752688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3466
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