Myeloperoxidase and Eosinophil Peroxidase Inhibit Endotoxin Activity and Increase Mouse Survival in a Lipopolysaccharide Lethal Dose 90% Model

Myeloperoxidase (MPO) and eosinophil peroxidase (EPO) are cationic haloperoxidases with potent microbicidal and detoxifying activities. MPO selectively binds to and kills some Gram-positive bacteria (GPB) and all Gram-negative bacteria (GNB) tested. GNB contain endotoxin, i.e., lipopolysaccharide (L...

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Bibliographic Details
Published in:J Immunol Res
Main Authors: Allen, Robert C., Henery, Mary L., Allen, John C., Hawks, Roger J., Stephens, Jackson T.
Format: Artigo
Language:Inglês
Published: Hindawi 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791248/
https://ncbi.nlm.nih.gov/pubmed/31663003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4783018
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