Bromofatty aldehyde derived from bromine exposure and myeloperoxidase and eosinophil peroxidase modify GSH and protein

α-Chlorofatty aldehydes (α-ClFALDs) and α-bromofatty aldehydes (α-BrFALDs) are produced in activated neutrophils and eosinophils. This study investigated the ability of α-BrFALD and α-ClFALD to react with the thiols of GSH and protein cysteinyl residues. Initial studies showed that 2-bromohexadecana...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Lipid Res
Auteurs principaux: Duerr, Mark A., Palladino, Elisa N. D., Hartman, Celine L., Lambert, James A., Franke, Jacob D., Albert, Carolyn J., Matalon, Sadis, Patel, Rakesh P., Slungaard, Arne, Ford, David A.
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2018
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880502/
https://ncbi.nlm.nih.gov/pubmed/29444934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M083279
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