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Peroxidasin and eosinophil peroxidase, but not myeloperoxidase, contribute to renal fibrosis in the murine unilateral ureteral obstruction model

Renal fibrosis is the pathological hallmark of chronic kidney disease (CKD) and manifests as glomerulosclerosis and tubulointerstitial fibrosis. Reactive oxygen species contribute significantly to renal inflammation and fibrosis, but most research has focused on superoxide and hydrogen peroxide (H(2...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Colon, Selene, Luan, Haiyan, Liu, Yan, Meyer, Cameron, Gewin, Leslie, Bhave, Gautam
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397377/
https://ncbi.nlm.nih.gov/pubmed/30565999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00291.2018
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