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Design, synthesis and evaluation of cytotoxic, antimicrobial, and anti-HIV-1 activities of new 1,2,3,4-tetrahydropyrimidine derivatives

A series of new 1,2,3,4-tetrahydropyrimidine (THPM) derivatives were designed and synthesized within a one-pot three component Biginelli reaction. The structures of compounds were characterized by FT-IR, 1HNMR, mass spectroscopy, and elemental analysis. All synthesized derivatives were screened for...

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Bibliographic Details
Published in:Res Pharm Sci
Main Authors: Razzaghi-Asl, Nima, Kamrani-Moghadam, Mahsa, Farhangi, Behzad, Vahabpour, Rouhollah, Zabihollahi, Rezvan, Sepehri, Saghi
Format: Artigo
Language:Inglês
Published: Wolters Kluwer - Medknow 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791171/
https://ncbi.nlm.nih.gov/pubmed/31620192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.253363
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