Novel 9-(alkylthio)-Acenaphtho[1,2-e]-1,2,4-triazine derivatives: synthesis, cytotoxic activity and molecular docking studies on B-cell lymphoma 2 (Bcl-2)

BACKGROUND AND PURPOSE OF THE STUDY: Acenaphtho derivatives have been reported as antitumor agents. Due to this fact and also with the aim of developing the chemistry of potentially bioactive heterocyclic compounds via efficient reactions, a facile procedure for the synthesis of 9-(alkylthio)-acenap...

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Détails bibliographiques
Auteurs principaux: Mohammadi, Mohammad K, Firuzi, Omidreza, Khoshneviszadeh, Mehdi, Razzaghi-Asl, Nima, Sepehri, Saghi, Miri, Ramin
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917598/
https://ncbi.nlm.nih.gov/pubmed/24393539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2008-2231-22-2
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