CD-340 functionalized doxorubicin-loaded nanoparticle induces apoptosis and reduces tumor volume along with drug-related cardiotoxicity in mice

BACKGROUND AND OBJECTIVE: Targeted drug delivery of nanoparticles decorated with site-specific recognition ligands is of considerable interest to minimize cytotoxicity of chemotherapeutics in the normal cells. The study was designed to develop CD-340 antibody-conjugated polylactic-co-glycolic acid (...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Mondal, Laboni, Mukherjee, Biswajit, Das, Kaushik, Bhattacharya, Sanchari, Dutta, Debasmita, Chakraborty, Shreyasi, Pal, Murari Mohan, Gaonkar, Raghuvir H, Debnath, Mita Chatterjee
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790403/
https://ncbi.nlm.nih.gov/pubmed/31632019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S220740
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