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HSP90 IN CANCER: TRANSCRIPTIONAL ROLES IN THE NUCLEUS

Hsp90 plays a key role in fostering metabolic pathways essential in tumorigenesis through its functions as a molecular chaperone. Multiple oncogenic factors in the membrane and cytoplasm are thus protected from degradation and destruction. Here we have considered Hsp90’s role in transcription in the...

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Detalhes bibliográficos
Publicado no:Adv Cancer Res
Main Authors: Calderwood, S. K., Neckers, L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790218/
https://ncbi.nlm.nih.gov/pubmed/26916002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.acr.2015.08.002
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