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The Prevalence of BRAF Mutations in Patients with Glioma: A Systematic Review

BACKGROUND: The V600mutation in the v-raf murine sarcoma oncogene homologue B1 (BRAF) enzyme, is a potential clinically actionable target in gliomas. BRAF inhibitors are in wide clinical use for other tumour types, particularly melanoma. The prevalence of this mutation across all gliomas is not full...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Samir Saincher, Saanwalshah, Higgins, Julian P T, McAleenan, Alexandra, Kurian, Kathreena M
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789687/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz167.056
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