Current Understanding of BRAF Alterations in Diagnosis, Prognosis, and Therapeutic Targeting in Pediatric Low-Grade Gliomas

The mitogen-activated protein kinase (MAPK) pathway is known to play a key role in the initiation and maintenance of many tumors as well as normal development. This often occurs through mutation of the genes encoding RAS and RAF proteins which are involved in signal transduction in this pathway. BRA...

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Detaylı Bibliyografya
Yayımlandı:Front Oncol
Asıl Yazarlar: Penman, Catherine Louise, Faulkner, Claire, Lowis, Stephen P., Kurian, Kathreena M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2015
Konular:
Oncology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347423/
https://ncbi.nlm.nih.gov/pubmed/25785246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00054
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