Immunogenicity and Protection Efficacy of a Naked Self-Replicating mRNA-Based Zika Virus Vaccine

To combat emerging infectious diseases like Zika virus (ZIKV), synthetic messenger RNAs (mRNAs) encoding viral antigens are very attractive as they allow a rapid, generic, and flexible production of vaccines. In this work, we engineered a self-replicating mRNA (sr-mRNA) vaccine encoding the pre-memb...

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Bibliografiska uppgifter
I publikationen:Vaccines (Basel)
Huvudupphovsmän: Zhong, Zifu, Portela Catani, João Paulo, Mc Cafferty, Séan, Couck, Liesbeth, Van Den Broeck, Wim, Gorlé, Nina, Vandenbroucke, Roosmarijn E., Devriendt, Bert, Ulbert, Sebastian, Cnops, Lieselotte, Michels, Johan, Ariën, Kevin K., Sanders, Niek N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789535/
https://ncbi.nlm.nih.gov/pubmed/31450775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines7030096
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