High Positive Correlations between ANRIL and p16-CDKN2A/p15-CDKN2B/p14-ARF Gene Cluster Overexpression in Multi-Tumor Types Suggest Deregulated Activation of an ANRIL–ARF Bidirectional Promoter

The CDKN2B-AS1 gene, also called ANRIL, is located at the human CDKN2A/B locus at 9p21.3 and transcribed by RNA polymerase II into a long non-coding RNA of 3834 bp. The CDKN2B-AS1 gene overlaps a critical region of 125 kb covering the CDKN2B gene. The CDKN2A/B locus encompasses three major tumor sup...

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Detalhes bibliográficos
Publicado no:Noncoding RNA
Main Authors: Drak Alsibai, Kinan, Vacher, Sophie, Meseure, Didier, Nicolas, Andre, Lae, Marick, Schnitzler, Anne, Chemlali, Walid, Cros, Jerome, Longchampt, Elisabeth, Cacheux, Wulfran, Pignot, Geraldine, Callens, Celine, Pasmant, Eric, Allory, Yves, Bieche, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789474/
https://ncbi.nlm.nih.gov/pubmed/31438464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ncrna5030044
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