High Positive Correlations between <i>ANRIL</i> and <i>p16</i>-<i>CDKN2A</i>/<i>p15</i>-<i>CDKN2B</i>/<i>p14</i>-<i>ARF</i> Gene Cluster Overexpression in Multi-Tumor Types Suggest Deregulated Activation of an <i>ANRIL–ARF</i> Bidirectional Promoter

The <i>CDKN2B-AS1</i> gene, also called <i>ANRIL</i>, is located at the human <i>CDKN2A/B</i> locus at 9p21.3 and transcribed by RNA polymerase II into a long non-coding RNA of 3834 bp. The <i>CDKN2B-AS1</i> gene overlaps a critical region of 125 kb co...

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Detalhes bibliográficos
Main Authors: Kinan Drak Alsibai, Sophie Vacher, Didier Meseure, Andre Nicolas, Marick Lae, Anne Schnitzler, Walid Chemlali, Jerome Cros, Elisabeth Longchampt, Wulfran Cacheux, Geraldine Pignot, Celine Callens, Eric Pasmant, Yves Allory, Ivan Bieche
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-08-01
Colecção:Non-Coding RNA
Assuntos:
lncRNA
<i>ANRIL</i> overexpression
<i>p16-CDKN2A/p15-CDKN2B/p14-ARF</i> cluster
Acesso em linha:https://www.mdpi.com/2311-553X/5/3/44
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