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Long Noncoding RNAs as New Architects in Cancer Epigenetics, Prognostic Biomarkers, and Potential Therapeutic Targets

Recent advances in genome-wide analysis have revealed that 66% of the genome is actively transcribed into noncoding RNAs (ncRNAs) while less than 2% of the sequences encode proteins. Among ncRNAs, high-resolution microarray and massively parallel sequencing technologies have identified long ncRNAs (...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Meseure, Didier, Drak Alsibai, Kinan, Nicolas, Andre, Bieche, Ivan, Morillon, Antonin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584070/
https://ncbi.nlm.nih.gov/pubmed/26448935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/320214
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