Effect of Sulforaphane and 5-Aza-2’-Deoxycytidine on Melanoma Cell Growth

Background: UV exposure-induced oxidative stress is implicated as a driving mechanism for melanoma. Increased oxidative stress results in DNA damage and epigenetic dysregulation. Accordingly, we explored whether a low dose of the antioxidant sulforaphane (SFN) in combination with the epigenetic drug...

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Bibliografiske detaljer
Udgivet i:Medicines (Basel)
Main Authors: Chiang, Tung-chin, Koss, Brian, Su, L. Joseph, Washam, Charity L., Byrum, Stephanie D., Storey, Aaron, Tackett, Alan J.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789461/
https://ncbi.nlm.nih.gov/pubmed/31252639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicines6030071
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