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Loss of E-cadherin inhibits CD103 anti-tumor activity and reduces checkpoint blockade responsiveness in melanoma

Identifying controlling features of responsiveness to checkpoint blockade therapies is an urgent goal in oncology research. Our group and others have previously shown melanoma tumors resistant to checkpoint blockade display features of mesenchymal transition including E-cadherin loss. Here, we prese...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Shields, Bradley D., Koss, Brian, Taylor, Erin M., Storey, Aaron J., West, Kirk L., Byrum, Stephanie D., Mackintosh, Samuel G., Edmondson, Rick, Mahmoud, Fade, Shalin, Sara C., Tackett, Alan J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420873/
https://ncbi.nlm.nih.gov/pubmed/30674537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-1722
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