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ANGPTL2 regulates autophagy through the MEK/ERK/Nrf-1 pathway and affects the progression of renal fibrosis in diabetic nephropathy

Background: Diabetic nephropathy (DN) is one of the most important microvascular complications of diabetes mellitus. The present study aims to explore whether angiopoietin-like protein 2 (ANGPTL2) can promote renal tissue fibrosis in DN. Materials and methods: Models includes diabetic SD rats induce...

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Publicat a:Am J Transl Res
Autors principals: Huang, Haiquan, Ni, Haifeng, Ma, Kunling, Zou, Jihong
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789235/
https://ncbi.nlm.nih.gov/pubmed/31632523
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