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m6A demethylase FTO promotes hepatocellular carcinoma tumorigenesis via mediating PKM2 demethylation

N6-methyladenosine (m6A) acts as the most common mRNA modification in mammal cells. Fat Mass and Obesity-associated protein (FTO) is the firstly identified demethylase in the m6A modification. This research tries to discover the potential roles of FTO in the m6A modification in the hepatocellular ca...

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Detalles Bibliográficos
Publicado en:Am J Transl Res
Main Authors: Li, Jie, Zhu, Lijun, Shi, Yanhong, Liu, Jingnan, Lin, Lin, Chen, Xi
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789218/
https://ncbi.nlm.nih.gov/pubmed/31632576
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