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Structural basis for substrate specificity and regulation of nucleotide sugar transporters in the lipid bilayer

Nucleotide sugars are the activated form of monosaccharides used by glycosyltransferases during glycosylation. In eukaryotes the SLC35 family of solute carriers are responsible for their selective uptake into the Endoplasmic Reticulum or Golgi apparatus. The structure of the yeast GDP-mannose transp...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Parker, Joanne L., Corey, Robin A., Stansfeld, Phillip J., Newstead, Simon
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789118/
https://ncbi.nlm.nih.gov/pubmed/31604945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12673-w
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