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Structural basis for substrate specificity and regulation of nucleotide sugar transporters in the lipid bilayer

Nucleotide sugars are the activated form of monosaccharides used by glycosyltransferases during glycosylation. In eukaryotes the SLC35 family of solute carriers are responsible for their selective uptake into the Endoplasmic Reticulum or Golgi apparatus. The structure of the yeast GDP-mannose transp...

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Udgivet i:Nat Commun
Main Authors: Parker, Joanne L., Corey, Robin A., Stansfeld, Phillip J., Newstead, Simon
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789118/
https://ncbi.nlm.nih.gov/pubmed/31604945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12673-w
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