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Nanoscale electrostatic gating of molecular transport through nuclear pore complexes as probed by scanning electrochemical microscopy

The nuclear pore complex (NPC) is a large protein nanopore that solely mediates molecular transport between the nucleus and cytoplasm of a eukaryotic cell. There is a long-standing consensus that selective transport barriers of the NPC are exclusively based on hydrophobic repeats of phenylalanine an...

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Publicado en:Chem Sci
Autores principales: Pathirathna, Pavithra, Balla, Ryan J., Meng, Guanqun, Wei, Zemeng, Amemiya, Shigeru
Formato: Artigo
Lenguaje:Inglês
Publicado: Royal Society of Chemistry 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6788534/
https://ncbi.nlm.nih.gov/pubmed/31673318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc02356a
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