Beta‐elemene inhibits breast cancer metastasis through blocking pyruvate kinase M2 dimerization and nuclear translocation

Pyruvate kinase M2 (PKM2), playing a central role in regulating aerobic glycolysis, was considered as a promising target for cancer therapy. However, its role in cancer metastasis is rarely known. Here, we found a tight relationship between PKM2 and breast cancer metastasis, demonstrated by the find...

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發表在:J Cell Mol Med
Main Authors: Pan, Yanhong, Wang, Wei, Huang, Shuai, Ni, Wenting, Wei, Zhonghong, Cao, Yuzhu, Yu, Suyun, Jia, Qi, Wu, Yuanyuan, Chai, Chuan, Zheng, Qian, Zhang, Lei, Wang, Aiyun, Sun, Zhiguang, Huang, Shile, Wang, Shijun, Chen, Wenxing, Lu, Yin
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
主題:
Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787513/
https://ncbi.nlm.nih.gov/pubmed/31343107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14568
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