An Evaluation of DNA Methyltransferase 1 (DNMT1) Single Nucleotide Polymorphisms and Chemotherapy-Associated Cognitive Impairment: A Prospective, Longitudinal Study

Strong evidence suggests that genetic variations in DNA methyltransferases (DNMTs) may alter the downstream expression and DNA methylation patterns of neuronal genes and influence cognition. This study investigates the association between a DNMT1 polymorphism, rs2162560, and chemotherapy-associated...

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Udgivet i:Sci Rep
Main Authors: Chan, Alexandre, Yeo, Angie, Shwe, Maung, Tan, Chia Jie, Foo, Koon Mian, Chu, Pat, Khor, Chiea Chuen, Ho, Han Kiat
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787348/
https://ncbi.nlm.nih.gov/pubmed/31601979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51203-y
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