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Curvature induction and sensing of the F-BAR protein Pacsin1 on lipid membranes via molecular dynamics simulations

F-Bin/Amphiphysin/Rvs (F-BAR) domain proteins play essential roles in biological processes that involve membrane remodelling, such as endocytosis and exocytosis. It has been shown that such proteins transform the lipid membrane into tubes. Notably, Pacsin1 from the Pacsin/Syndapin subfamily has the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mahmood, Md. Iqbal, Noguchi, Hiroshi, Okazaki, Kei-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787258/
https://ncbi.nlm.nih.gov/pubmed/31601944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51202-z
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