The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site

The Caulobacter crescentus cell cycle-regulated DNA methyltransferase (CcrM) methylates the adenine of hemimethylated GANTC after replication. Here we present the structure of CcrM in complex with double-stranded DNA containing the recognition sequence. CcrM contains an N-terminal methyltransferase...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Horton, John R., Woodcock, Clayton B., Opot, Sifa B., Reich, Norbert O., Zhang, Xing, Cheng, Xiaodong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787082/
https://ncbi.nlm.nih.gov/pubmed/31601797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12498-7
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