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Proximal Recognition Sites Facilitate Intrasite Hopping by DNA Adenine Methyltransferase: MECHANISTIC EXPLORATION OF EPIGENETIC GENE REGULATION
The methylation of adenine in palindromic 5′-GATC-3′ sites by Escherichia coli Dam supports diverse roles, including the essential regulation of virulence genes in several human pathogens. As a result of a unique hopping mechanism, Dam methylates both strands of the same site prior to fully dissocia...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3391122/ https://ncbi.nlm.nih.gov/pubmed/22570478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.332502 |
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