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Proximal Recognition Sites Facilitate Intrasite Hopping by DNA Adenine Methyltransferase: MECHANISTIC EXPLORATION OF EPIGENETIC GENE REGULATION

The methylation of adenine in palindromic 5′-GATC-3′ sites by Escherichia coli Dam supports diverse roles, including the essential regulation of virulence genes in several human pathogens. As a result of a unique hopping mechanism, Dam methylates both strands of the same site prior to fully dissocia...

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מידע ביבליוגרפי
Main Authors: Pollak, Adam J., Reich, Norbert O.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391122/
https://ncbi.nlm.nih.gov/pubmed/22570478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.332502
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