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DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G(2)-checkpoint in S-phase irradiated cells

We previously reported that cells exposed to low doses of ionizing radiation (IR) in the G(2)-phase of the cell cycle activate a checkpoint that is epistatically regulated by ATM and ATR operating as an integrated module. In this module, ATR interphases exclusively with the cell cycle to implement t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Mladenov, Emil, Fan, Xiaoxiang, Paul-Konietzko, Katja, Soni, Aashish, Iliakis, George
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787047/
https://ncbi.nlm.nih.gov/pubmed/31601897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51071-6
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