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Low-grade glioma harbors few CD8 T cells, which is accompanied by decreased expression of chemo-attractants, not immunogenic antigens

In multiple tumor types, prediction of response to immune therapies relates to the presence, distribution and activation state of tumor infiltrating lymphocytes (TILs). Although such therapies are, to date, unsuccessful in gliomas, little is known on the immune contexture of TILs in these tumors. We...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Weenink, Bas, Draaisma, Kaspar, Ooi, Han Z., Kros, Johan M., Sillevis Smitt, Peter A. E., Debets, Reno, French, Pim J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787014/
https://ncbi.nlm.nih.gov/pubmed/31601888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51063-6
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