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Lack of B and T cell reactivity towards IDH1(R132H) in blood and tumor tissue from LGG patients
PURPOSE: Mutations in the isocitrate dehydrogenase-1 gene (IDH1) occur at high frequency in grade II–III gliomas (LGGs). IDH1 mutations are somatic, missense and heterozygous affecting codon 132 in the catalytic pocket of the enzyme. In LGG, most mutations (90%) result in an arginine to histidine su...
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| 出版年: | J Neurooncol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer US
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6660510/ https://ncbi.nlm.nih.gov/pubmed/31240524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-019-03228-6 |
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