Gabapentin alleviates chronic spontaneous pain and acute hypoxia-related pain in a mouse model of sickle cell disease

Pain is the main complication of sickle cell disease (SCD). Individuals with SCD experience acute pain episodes and chronic daily pain, both of which are managed with opioids. Opioids have deleterious side effects and use-associated stigma that make them less than ideal for SCD pain management. Afte...

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Veröffentlicht in:Br J Haematol
Hauptverfasser: Sadler, Katelyn E., Langer, Sarah N., Menzel, Anthony D., Moehring, Francie, Erb, Ashley N., Brandow, Amanda M., Stucky, Cheryl L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786911/
https://ncbi.nlm.nih.gov/pubmed/31247672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.16067
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