Role of TRPM8 Channels in Altered Cold Sensitivity of Corneal Primary Sensory Neurons Induced by Axonal Damage

The cornea is extensively innervated by trigeminal ganglion cold thermoreceptor neurons expressing TRPM8 (transient receptor potential cation channel subfamily M member 8). These neurons respond to cooling, hyperosmolarity and wetness of the corneal surface. Surgical injury of corneal nerve fibers a...

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Publicado en:J Neurosci
Autores principales: Piña, Ricardo, Ugarte, Gonzalo, Campos, Matías, Íñigo-Portugués, Almudena, Olivares, Erick, Orio, Patricio, Belmonte, Carlos, Bacigalupo, Juan, Madrid, Rodolfo
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2019
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786815/
https://ncbi.nlm.nih.gov/pubmed/31471469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0654-19.2019
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