Atlas of Subcellular RNA Localization Revealed by APEX-seq

We introduce APEX-seq, a method for RNA sequencing based on direct proximity labeling of RNA using the peroxidase enzyme APEX2. APEX-seq in nine distinct subcellular locales produced a nanometer-resolution spatial map of the human transcriptome as a resource, revealing extensive patterns of localiza...

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Publicat a:Cell
Autors principals: Fazal, Furqan M., Han, Shuo, Parker, Kevin R., Kaewsapsak, Pornchai, Xu, Jin, Boettiger, Alistair N., Chang, Howard Y., Ting, Alice Y.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786773/
https://ncbi.nlm.nih.gov/pubmed/31230715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.05.027
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