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Plasma mitochondrial DNA is elevated in obese type 2 diabetes mellitus patients and correlates positively with insulin resistance

Cells damaged by mechanical or infectious injury release proinflammatory mitochondrial DNA (mtDNA) fragments into the circulation. We evaluated the relation between plasma levels of mtDNA fragments in obese type 2 diabetes mellitus (T2DM) patients and measures of chronic inflammation and insulin res...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yuzefovych, Larysa V., Pastukh, Viktor M., Ruchko, Mykhaylo V., Simmons, Jon D., Richards, William O., Rachek, Lyudmila I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786592/
https://ncbi.nlm.nih.gov/pubmed/31600210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222278
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