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Osthole prevents tamoxifen-induced liver injury in mice

Tamoxifen (TMX) is an antiestrogen drug that is used in the treatment and prevention of all stages of estrogen-dependent breast cancer. Adverse effects of TMX include hepatotoxicity. In this study, we investigated the therapeutic effects of osthole, isolated from medicinal plants especially Fructus...

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Dettagli Bibliografici
Pubblicato in:Acta Pharmacol Sin
Autori principali: Zhou, Wen-bo, Zhang, Xin-xin, Cai, Yun, Sun, Wu, Li, Hao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786423/
https://ncbi.nlm.nih.gov/pubmed/30315252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0171-y
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