Minocycline protects against myocardial ischemia/reperfusion injury in rats by upregulating MCPIP1 to inhibit NF-κB activation

Minocycline is a tetracycline antibiotic and has been shown to play a protective role in cerebral and myocardial ischemia/reperfusion (I/R). However, the underlying mechanism remains unclear. Herein, we investigated whether monocyte chemotactic protein-induced protein-1 (MCPIP1), a negative regulato...

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Veröffentlicht in:Acta Pharmacol Sin
Hauptverfasser: Yi, Quan, Tan, Fang-hui, Tan, Jia-an, Chen, Xiu-hui, Xiao, Qing, Liu, Ying-hua, Zhang, Gui-ping, Luo, Jian-dong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786388/
https://ncbi.nlm.nih.gov/pubmed/30792486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0214-z
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