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Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice

The pathogenesis of Alzheimer's disease (AD) is characterized by both accumulation of β-amyloid (Aβ) plaque and formation of neurofibrillary tangles in the brain. Recent evidence shows that autophagy activation may potently promote intracellular Aβ clearance. Thus targeting autophagy becomes a...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Fan, Lei, Qiu, Xiao-xia, Zhu, Zhi-yuan, Lv, Jian-lu, Lu, Jian, Mao, Fei, Zhu, Jin, Wang, Jia-ying, Guan, Xiao-wei, Chen, Jing, Ren, Jin, Ye, Ji-ming, Zhao, Yong-hua, Li, Jian, Shen, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786387/
https://ncbi.nlm.nih.gov/pubmed/31000769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0220-1
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