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µ-TRTX-Ca1a: a novel neurotoxin from Cyriopagopus albostriatus with analgesic effects

Human genetic and pharmacological studies have demonstrated that voltage-gated sodium channels (VGSCs) are promising therapeutic targets for the treatment of pain. Spider venom contains many toxins that modulate the activity of VGSCs. To date, only 0.01% of such spider toxins has been explored, and...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Zhang, Yun-xiao, Peng, De-zheng, Zhang, Qing-feng, Huang, Biao, Yang, Qiu-chu, Tang, Dong-fang, Chen, Min-zhi, Rong, Ming-qiang, Liu, Zhong-hua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786292/
https://ncbi.nlm.nih.gov/pubmed/30382183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0181-9
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