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Effect of Off-Target Binding on (18)F-Flortaucipir Variability in Healthy Controls Across the Life Span
Measuring early tau accumulation is important in studying aging and Alzheimer disease and is only as accurate as the signal-to-noise ratio of the tracer. Along with aggregated tau in the form of neurofibrillary tangles, (18)F-flortaucipir has been reported to bind to neuromelanin, monoamine oxidase,...
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| Pubblicato in: | J Nucl Med |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society of Nuclear Medicine
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6785795/ https://ncbi.nlm.nih.gov/pubmed/30877180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.224113 |
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