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Effect of Off-Target Binding on (18)F-Flortaucipir Variability in Healthy Controls Across the Life Span

Measuring early tau accumulation is important in studying aging and Alzheimer disease and is only as accurate as the signal-to-noise ratio of the tracer. Along with aggregated tau in the form of neurofibrillary tangles, (18)F-flortaucipir has been reported to bind to neuromelanin, monoamine oxidase,...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Baker, Suzanne L., Harrison, Theresa M., Maass, Anne, La Joie, Renaud, Jagust, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Nuclear Medicine 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785795/
https://ncbi.nlm.nih.gov/pubmed/30877180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.224113
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