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Senescent HUVECs-secreted exosomes trigger endothelial barrier dysfunction in young endothelial cells
Accumulation of senescent endothelial cells can cause endothelium dysfunction which eventually leads to age-related vascular disorders. The senescent-associated secretory phenotype (SASP) cells secrete a plethora of soluble factors that negatively influence the surrounding tissue microenvironment. T...
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| Publicado no: | EXCLI J |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Leibniz Research Centre for Working Environment and Human Factors
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6785768/ https://ncbi.nlm.nih.gov/pubmed/31611757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2019-1505 |
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