Up-regulation of miR-381 inhibits NAD+ salvage pathway and promotes apoptosis in breast cancer cells

Nicotinamide phosphoribosyltransferase (NAMPT), a rate-limiting enzyme involved in nicotinamide adenine dinucleotide (NAD) salvage pathway, is overexpressed in many human malignancies such as breast cancer. This enzyme plays a critical role in survival and growth of cancer cells. MicroRNAs (miRNAs)...

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Veröffentlicht in:EXCLI J
Hauptverfasser: Bolandghamat Pour, Zahra, Nourbakhsh, Mitra, Mousavizadeh, Kazem, Madjd, Zahra, Ghorbanhosseini, Seyedeh Sara, Abdolvahabi, Zohreh, Hesari, Zahra, Mobaser, Samira Ezzati
Format: Artigo
Sprache:Inglês
Veröffentlicht: Leibniz Research Centre for Working Environment and Human Factors 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785761/
https://ncbi.nlm.nih.gov/pubmed/31611752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2019-1431
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