Suppression of nicotinamide phosphoribosyltransferase expression by miR-154 reduces the viability of breast cancer cells and increases their susceptibility to doxorubicin

Abstract Background Nicotinamide phosphoribosyltransferase (NAMPT) enzyme acts as the major enzyme in the nicotinamide adenine dinucleotide (NAD) synthesis salvage pathway. Deregulation of NAD could be associated with progression of several cancers such as breast cancer. Here, the consequence of NAM...

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Main Authors: Zahra Bolandghamat Pour, Mitra Nourbakhsh, Kazem Mousavizadeh, Zahra Madjd, Seyedeh Sara Ghorbanhosseini, Zohreh Abdolvahabi, Zahra Hesari, Samira Ezzati Mobasser
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-11-01
Colecção:BMC Cancer
Assuntos:
Nicotinamide phosphoribosyltransferase
Breast cancer
miR-154
Doxorubicin
microRNA
Acesso em linha:http://link.springer.com/article/10.1186/s12885-019-6221-0
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