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The role of polygenic risk score gene-set analysis in the context of the omnigenic model of schizophrenia

A recent development in the genetic architecture of schizophrenia suggested that an omnigenic model may underlie the risk for this disorder. The aim of our study was to use polygenic profile scoring to quantitatively assess whether a number of experimentally derived sets would contribute to the diso...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Rammos, Alexandros, Gonzalez, Lara A. Neira, Weinberger, Daniel R., Mitchell, Kevin J., Nicodemus, Kristin K.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785707/
https://ncbi.nlm.nih.gov/pubmed/31078131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0410-z
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