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l-DOPA and Its Receptor GPR143: Implications for Pathogenesis and Therapy in Parkinson’s Disease

l-3,4-Dihydroxyphenylalanine (l-DOPA) is the most effective therapeutic agent for Parkinson’s disease (PD). l-DOPA is traditionally believed to be an inert amino acid that exerts actions and effectiveness in PD through its conversion to dopamine. In contrast to this generally accepted idea, l-DOPA i...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Goshima, Yoshio, Masukawa, Daiki, Kasahara, Yuka, Hashimoto, Tatsuo, Aladeokin, Aderemi Caleb
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785630/
https://ncbi.nlm.nih.gov/pubmed/31632270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01119
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