L-DOPA sensitizes vasomotor tone by modulating the vascular alpha1-adrenergic receptor

Blood pressure is regulated by extrinsic factors including noradrenaline, the sympathetic neurotransmitter that controls cardiovascular functions through adrenergic receptors. However, the fine-tuning system of noradrenaline signaling is relatively unknown. We here show that l-3,4-dihydroxyphenylala...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Masukawa, Daiki, Koga, Motokazu, Sezaki, Anna, Nakao, Yuka, Kamikubo, Yuji, Hashimoto, Tatsuo, Okuyama-Oki, Yuki, Aladeokin, Aderemi Caleb, Nakamura, Fumio, Yokoyama, Utako, Wakui, Hiromichi, Ichinose, Hiroshi, Sakurai, Takashi, Umemura, Satoshi, Tamura, Koichi, Ishikawa, Yoshihiro, Goshima, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621878/
https://ncbi.nlm.nih.gov/pubmed/28931752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90903
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