Genome‐wide meta‐analysis of SNP and antihypertensive medication interactions on left ventricular traits in African Americans

BACKGROUND: Left ventricular (LV) hypertrophy affects up to 43% of African Americans (AAs). Antihypertensive treatment reduces LV mass (LVM). However, interindividual variation in LV traits in response to antihypertensive treatments exists. We hypothesized that genetic variants may modify the associ...

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Publicat a:Mol Genet Genomic Med
Autors principals: Do, Anh N., Zhao, Wei, Baldridge, Abigail S., Raffield, Laura M., Wiggins, Kerri L., Shah, Sanjiv J., Aslibekyan, Stella, Tiwari, Hemant K., Limdi, Nita, Zhi, Degui, Sitlani, Colleen M., Taylor, Kent D., Psaty, Bruce M., Sotoodehnia, Nona, Brody, Jennifer A., Rasmussen‐Torvik, Laura J., Lloyd‐Jones, Donald, Lange, Leslie A., Wilson, James G., Smith, Jennifer A., Kardia, Sharon L. R., Mosley, Thomas H., Vasan, Ramachandran S., Arnett, Donna K., Irvin, Marguerite R.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785453/
https://ncbi.nlm.nih.gov/pubmed/31407531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.788
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