The Carcinogenome Project: In Vitro Gene Expression Profiling of Chemical Perturbations to Predict Long-Term Carcinogenicity

BACKGROUND: Most chemicals in commerce have not been evaluated for their carcinogenic potential. The de facto gold-standard approach to carcinogen testing adopts the 2-y rodent bioassay, a time-consuming and costly procedure. High-throughput in vitro assays are a promising alternative for addressing...

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Publicado en:Environ Health Perspect
Main Authors: Li, Amy, Lu, Xiaodong, Natoli, Ted, Bittker, Joshua, Sipes, Nisha S., Subramanian, Aravind, Auerbach, Scott, Sherr, David H., Monti, Stefano
Formato: Artigo
Idioma:Inglês
Publicado: Environmental Health Perspectives 2019
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785232/
https://ncbi.nlm.nih.gov/pubmed/30964323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP3986
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